Zverev, the No. 2 seed, easily defeated Carabelli. Draper (No. 5) beat Darderi, saving all break points. Italian Musetti (No. 8) won his match, and Italian wildcard Passaro upset Dimitrov (No. 14). Rune (No. 9) and Medvedev (No. 10) also advanced. Other winners included Fils, Tsitsipas, Khachanov, and Popyrin. Nakashima advanced via walkover, and Moutet progressed due to Humbert's retirement.
